Brugnara, LauraMurillo, SerafínNovials, AnnaRojo-Martínez, GemmaSoriguer, FedericoGoday, AlbertCalle-Pascual, AlfonsoCastaño, LuisGaztambide, SoniaValdés, SergioFranch, JosepCastell, ConxaVendrell, JoanCasamitjana, RoserBosch-Comas, AnnaBordiú, ElenaCarmena, RafaelCatalá, MiguelDelgado, EliasGirbés, JuanLópez-Alba, AlfonsoMartínez-Larrad, Maria TeresaMenéndez, EdelmiroMora-Peces, InmaculadaPascual-Manich, GemmaSerrano-Ríos, ManuelGomis, RamonOrtega, Emilio2016-10-052016-10-052016-08-17Brugnara L, Murillo S, Novials A, Rojo-Martínez G, Soriguer F, Goday A, et al. Low Physical Activity and Its Association with Diabetes and Other Cardiovascular Risk Factors: A Nationwide, Population-Based Study. PLoS ONE. 2016; 11(8):e0160959http://hdl.handle.net/10668/2446Journal Article;Low physical activity (PA), or sedentary lifestyle, is associated with the development of several chronic diseases. We aimed to investigate current prevalence of sedentariness and its association with diabetes and other cardiovascular risk factors. PA was evaluated in a population-based, cross-sectional, randomly sampled study conducted in 2009-2010 in Spain. International Physical Activity Questionnaire (SF-IPAQ) was used to assess PA. 4991 individuals (median age 50 years, 57% women) were studied. Prevalence of sedentariness was 32.3% for men and 39% for women (p < 0.0001). Sex differences were particularly notable (age*sex interaction, p = 0.0024) at early and older ages. Sedentary individuals had higher BMI (28 vs. 27 kg/m2) and obesity prevalence (37 vs. 26%). Low PA was present in 44, 43, and 38% of individuals with known diabetes (KDM), prediabetes/unknown-diabetes (PREDM/UKDM), and normal glucose regulation (p = 0.0014), respectively. No difference between KDM and PREDM/UKDM (p = 0.72) was found. Variables independently associated (p < 0.05) with sedentariness were age, sex, BMI, central obesity, Mediterranean diet adherence, smoking habit, HDL-cholesterol, triglycerides and dyslipidemia. Low PA is on the rise in Spain, especially among women. Sedentariness is associated with several cardiovascular risk factors and may be responsible for the increasing prevalence of obesity and diabetes in this country.enÍndice de masa corporalEnfermedades cardiovascularesHDL-colesterolEnfermedad crónicaEstudios transversalesDieta mediterráneaDislipidemiasGlucosaActividad motoraObesidadObesidad abdominalEstado prediabéticoPrevalenciaFactores de riesgoVida sedentariaHábito de fumarEspañaEncuestas y cuestionariosTriglicéridosMedical Subject Headings::Chemicals and Drugs::Lipids::Lipoproteins::Lipoproteins, HDL::Cholesterol, HDLMedical Subject Headings::Diseases::Cardiovascular DiseasesMedical Subject Headings::Chemicals and Drugs::Lipids::Lipoproteins::Lipoproteins, HDL::Cholesterol, HDLMedical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic DiseaseMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional StudiesMedical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet::Diet, MediterraneanMedical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Lipid Metabolism Disorders::DyslipidemiasMedical Subject Headings::Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::GlucoseMedical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Movement::Motor ActivityMedical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::ObesityMedical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity::Obesity, AbdominalMedical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus::Prediabetic StateMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::PrevalenceMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk FactorsMedical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Life Style::Sedentary LifestyleMedical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Habits::SmokingMedical Subject Headings::Geographicals::Geographic Locations::Europe::SpainMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Surveys and QuestionnairesMedical Subject Headings::Chemicals and Drugs::Lipids::Glycerides::Triglyceridesresearch article27532610open access10.1371/journal.pone.01609591932-6203PMC4988632