Torres-Collado, LauraGarcia-de la Hera, ManuelaCano-Ibañez, NaomiBueno-Cavanillas, AuroraVioque, Jesus2023-05-032023-05-032022-04-08Torres-Collado L, García-de la Hera M, Cano-Ibañez N, Bueno-Cavanillas A, Vioque J. Association between Dietary Diversity and All-Cause Mortality: A Multivariable Model in a Mediterranean Population with 18 Years of Follow-Up. Nutrients. 2022 Apr 11;14(8):1583.http://hdl.handle.net/10668/21470We evaluated the relationship between the dietary diversity score (DDS) and all-cause, CVD and cancer mortality in an adult Mediterranean population. We analyzed the data of 1540 participants from the Valencia Nutrition Survey. The DDS was estimated using a validated food frequency questionnaire and was categorized into quartiles (Q), where the first quartile indicates the lowest dietary diversity. Deaths were ascertained during an 18-year follow-up period. Cox regression models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI). There were 403 deaths during the follow-up period (40% due to CVD). An inverse association was observed between the DDS and all-cause and CVD mortality. Compared with participants in the lowest DDS quartile (Q1), participants in the highest DDS quartile (Q4) showed 32% and 45% less risk of death for all-cause and CVD mortality, in sex- and age-adjusted models, respectively. Regarding the food groups in the DDS, an inverse association was identified between total vegetable consumption diversity and all-cause and CVD mortality in the highest quartiles, (Q3 vs. Q1, HR: 0.70; 95% CI: 0.50, 0.99) and (Q4 vs. Q1, HR: 0.52; 95% CI: 0.30, 0.91), respectively. This study suggests that a higher diversity in food intake, particularly in vegetables, may be associated with a lower risk of all-cause and CVD mortality. This association should be further investigated in other wider populations.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/cancercardiovascular diseasedietary diversity scoremortalityAdultCardiovascular DiseasesDietFollow-Up StudiesHumansNutrition SurveysProportional Hazards ModelsRisk FactorsVegetablesresearch article35458145open accessVerdurasModelos de riesgos proporcionalesHumanosFactores de riesgoEstudios de seguimientoEnfermedades cardiovascularesEncuestas nutricionalesDietaAdulto10.3390/nu140815832072-6643PMC9029508https://www.mdpi.com/2072-6643/14/8/1583/pdf?version=1649731589https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029508/pdf