Diagnostic Accuracy of the Panbio Severe Acute Respiratory Syndrome Coronavirus 2 Antigen Rapid Test Compared with Reverse-Transcriptase Polymerase Chain Reaction Testing of Nasopharyngeal Samples in the Pediatric Population.

Villaverde, SerenaDomínguez-Rodríguez, SaraSabrido, GemaPérez-Jorge, ConchitaPlata, MartaRomero, María PilarGrasa, Carlos DanielJiménez, Ana BelénHeras, ElenaBroncano, AntonioNúñez, María Del MarIllán, MartaMerino, PalomaSoto, BeatrizMolina-Arana, DavidBermejo, AmandaMendoza, PabloGijón, ManuelPérez-Moneo, BegoñaMoraleda, CintaTagarro, AlfredoEpidemiological Study of COVID-19 in Children of the Spanish Society of Pediatric (EPICO-AEP) Working Group2023-02-092023-02-092021-01-21http://hdl.handle.net/10668/17027We conducted a multicenter clinical validity study of the Panbio coronavirus disease 2019 Antigen Rapid Test of nasopharyngeal samples in pediatric patients with coronavirus disease 2019-compatible symptoms of ≤5 days of evolution. Our study showed limited accuracy in nasopharyngeal antigen testing: overall sensitivity was 45.4%, and 99.8% of specificity, positive-predictive value was 92.5%.enCOVID-19PCRSARS-CoV-2antigen testAdolescentAntigens, ViralCOVID-19ChildChild, PreschoolDNA, ViralFemaleHumansInfantInfant, NewbornMaleNasopharynxPandemicsReproducibility of ResultsReverse Transcriptase Polymerase Chain ReactionSARS-CoV-2Diagnostic Accuracy of the Panbio Severe Acute Respiratory Syndrome Coronavirus 2 Antigen Rapid Test Compared with Reverse-Transcriptase Polymerase Chain Reaction Testing of Nasopharyngeal Samples in the Pediatric Population.research article33484697open access10.1016/j.jpeds.2021.01.0271097-6833PMC7826137http://www.jpeds.com/article/S0022347621000342/pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826137/pdf