Serrano, CarolinaLostalé, FernandoRodríguez-Panadero, FranciscoBlas, Ignacio deLaborda, Aliciade Gregorio, Miguel Angel2025-01-072025-01-072015-07-02https://hdl.handle.net/10668/27466The objective of this study was to assess tracheal reactivity after the deployment of different self-expandable metal stents (SEMS). Forty female New Zealand rabbits were divided into four groups. Three groups received three different SEMS: steel (ST), nitinol (NiTi), or nitinol drug-eluting stent (DES); the fourth group was the control group (no stent). Stents were deployed percutaneously under fluoroscopic guidance. Animals were assessed by multi-slice, computed tomography (CT) scans, and tracheas were collected for anatomical pathology (AP) study. Data from CT and AP were statistically analyzed and correlated. The DES group had the longest stenosis (20.51±14.08mm vs. 5.84±12.43 and 6.57±6.54mm in NiTi and ST, respectively, day 30; P The ST group developed granulomas and significant stenosis. NiTi was the least reactive stent, while DES caused significant lesions that may be related to drug dosage. This type of DES stent is therefore not recommended for the treatment of tracheobronchial stenosis.enAirway obstructionAnimal modelsDrug-eluting stentsEstenosis traquealExperimentación animalObstrucción de la vía aéreaStentsStents liberadores de fármacosTracheal stenosisAlloysAnimalsFemaleFluoroscopyGranulomaModels, AnimalMultidetector Computed TomographyRabbitsSelf Expandable Metallic StentsSteelTracheal DiseasesTracheal Stenosisresearch article2614178210.1016/j.arbres.2015.04.0121579-2129