Máiz, LGirón, ROlveira, CVendrell, MNieto, RMartínez-García, M A2023-01-252023-01-252016-08-22http://hdl.handle.net/10668/10384Data on the prevalence of and factors associated with nontuberculous mycobacteria (NTM) in patients with non-cystic fibrosis (CF) bronchiectasis are limited. Our aim was to determine the prevalence and factors associated with isolation of NTM in this population. We performed a multicenter observational study of historical cohorts comprising consecutive patients with non-CF bronchiectasis and at least 2 sputum samples cultured for mycobacteria over a period of 5 years. The study population included 218 adult patients (61.9 % women) with a mean (SD) age of 55.7 (16) years and a mean (SD) of 5.1 (3.3) cultures/patient. NTM was isolated from sputum in 18 patients (8.3 %). Of these, 5 patients (28 %) met the American Thoracic Society criteria for NTM disease. Mycobacterium avium complex was the most frequently isolated microorganism (9 patients, 4.1 %). The variables independently associated with isolation of NTM were FVC ≥ 75 % predicted (OR, 4.84; 95 % CI 1.47 to 15.9; p  A significant number of patients with non-CF bronchiectasis are positive for the isolation of NTM. M. avium complex is the most frequently isolated mycobacteria. FVC ≥ 75 % predicted, age ≥ 50 years, and a BMI ≤ 23 kg/m(2) were independently associated with the presence of NTM in patients with non-CF bronchiectasis.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Disease prevalenceEpidemiologyNon-cystic fibrosis bronchiectasisNontuberculous mycobacteriaAdultAge FactorsAgedBody Mass IndexBronchiectasisCystic FibrosisFemaleHumansMaleMiddle AgedMycobacterium Infections, NontuberculousMycobacterium avium ComplexNontuberculous MycobacteriaOdds RatioPrevalenceSputumTomography, X-Ray Computedresearch article27549788open access10.1186/s12879-016-1774-x1471-2334PMC4994165https://doi.org/10.1186/s12879-016-1774-xhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994165/pdf