Barge-Caballero, GonzaloCastel-Lavilla, María AAlmenar-Bonet, LuisGarrido-Bravo, Iris PDelgado, Juan FRangel-Sousa, DiegoGonzález-Costello, JoséSegovia-Cubero, JavierFarrero-Torres, MartaLambert-Rodríguez, José LuisCrespo-Leiro, María GHervás-Sotomayor, DanielaPortolés-Ocampo, AnaMartínez-Sellés, ManuelDe la Fuente-Galán, LuisRábago-Juan-Aracil, GregorioGonzález-Vílchez, FranciscoMirabet-Pérez, SoniaMuñiz, JavierBarge-Caballero, Eduardo2023-01-252023-01-252019http://hdl.handle.net/10668/14200To investigate the potential clinical benefit of an intra-aortic balloon pump (IABP) in patients supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO) as a bridge to heart transplantation (HT). We studied 169 patients who were listed for urgent HT under VA-ECMO support at 16 Spanish institutions from 2010 to 2015. The clinical outcomes of patients under simultaneous IABP support (n = 73) were compared to a control group of patients without IABP support (n = 96). There were no statistically significant differences between the IABP and control groups with regard to the cumulative rates of transplantation (71.2% vs 81.2%, P = 0.17), death during VA-ECMO support (20.6% vs 14.6%, P = 0.31), transition to a different mechanical circulatory support device (5.5% vs 5.2%, P = 0.94) or weaning from VA-ECMO support due to recovery (2.7% vs 0%, P = 0.10). There was a higher incidence of bleeding events in the IABP group (45.2% vs 25%, P = 0.006; adjusted odds ratio 2.18, 95% confidence interval 1.02-4.67). In-hospital postoperative mortality after HT was 34.6% in the IABP group and 32.5% in the control group (P = 0.80). One-year survival after listing for urgent HT was 53.3% in the IABP group and 52.2% in the control group (log rank P = 0.75). Multivariate adjustment for potential confounders did not change this result (adjusted hazard ratio 0.94, 95% confidence interval 0.56-1.58). In our study, simultaneous IABP therapy in transplant candidates under VA-ECMO support did not significantly reduce morbidity or mortality.enExtracorporeal membrane oxygenationHeart transplantationIntra-aortic balloon pumpExtracorporeal Membrane OxygenationFemaleHeart FailureHeart TransplantationHospital MortalityHumansIntra-Aortic Balloon PumpingMaleMiddle AgedOdds RatioRegistriesRetrospective StudiesSpainSurvival Rateresearch article31257414open access10.1093/icvts/ivz1551569-9285https://ruc.udc.es/dspace/bitstream/2183/26566/2/CrespoLeiro_2019_Venoarterial_extracorporeal_membrane_oxygenation.pdf