Lopez-Guerrero, J. A.Mendiola, M.Perez-Fidalgo, J. A.Romero, I.Gomez-Raposo, C.Herrero, A.Alarcon, J. D.Esteban-Esteban, C.Marquina-Ospina, G.Rubio, M. J.Sanchez, L.Guerra, E. M.Gonzalez-Martin, A.2025-01-072025-01-072020Guerrero JAL, Mendiola M, Pérez-Fidalgo JA, Romero I, Raposo CG, Herrero A, et al. 854P A multicenter clinical registry with associated biological samples of gynecological cancer patients: Pilot study of the Spanish Ovarian Cancer Research Group (GEICO 81-T). Annals Of Oncology [Internet]. 1 de septiembre de 2020;31:S635-60923-7534https://hdl.handle.net/10668/25338Background: Accurate clinical annotations associated with biological samples are crucial for outcome research on real-world data. This study aims to create a virtual clinical registry (VCR) of gynecological cancer patients, associated with the collection of biological samples through biobanks, to support real-world studies and translational research in Spain. Methods: GEICO VCR is an observational, prospective, multicenter study involving over 60 hospitals, integrating clinical information and biological samples into four cohorts: ovarian cancer (OC), endometrial cancer (EC), cervical cancer (CC), and rare cancers (RC). A pilot study implementing the OC module was conducted in nine centers. Inclusion criteria were: 1) women diagnosed with gynecological cancer since March 2019; 2) age ≥18 years; 3) written informed consent; and 4) access to medical records. Clinical information is collected across seven data sets: Patient data (anonymized), Diagnosis, Primary Surgery, Chemotherapy, Biobank, Recurrence, and Follow-up. Collected samples include formalin-fixed and paraffin-embedded material, fresh frozen tissues, serum and plasma, lymphocytes, and ascites, which are stored at each center’s biobank using a coding system that links the samples to clinical information.enPilot ProjectsTranslational Research, BiomedicalBiological Specimen BanksAscitesAscitesFormaldehydeFollow-Up StudiesParaffin EmbeddingSpainNeoplasmsconference outputRestricted AccessNeoplasiasProductos biológicosBancos de muestras biológicasAscitisQuimioterapiaCodificación clínica10.1016/j.annonc.2020.08.9931569-8041http://www.annalsofoncology.org/article/S0923753420409895/pdf573469101142