Coronel-Perez, Isabel MPorras-Gonzdlez, AnaRodriguez-Rey, Elena MCroche-Santander, Borja2023-01-252023-01-252019http://hdl.handle.net/10668/13430Hand-foot-mouth disease can present atypically, including forms with more numerous lesions and/or morphologically different from the classic presentation. It may even mimic other viral diseases. We present the case of a 2-year-old child previously diagnosed with atopic dermatitis, who presented with papules and umbilicated vesicles affecting the perioral area and limbs, predominantly in pressure areas, as well as in areas with previous atopic lesions. Although he was clinically diagnosed with herpetic eczema, tests results were negative for herpes virus. However, positive entorovirus polymerase chain reaction results were obtained from the content of a vesicle, a pharyngeal exudate and a stool sample.esAtypical handEnterovirusFoot and mouth diseaseUmbilicated vesiclesVesiculobullous exanthemaAcrodermatitisChild, PreschoolHand, Foot and Mouth DiseaseHumansKaposi Varicelliform EruptionMale[Infantile atypical hand-foot-mouth disease with features of eczema herpeticum and acrodermatitis].Enfermedad boca-mano-pie atÃpica infantil con rasgos de eczema herpetico y de acrodermatitis.research article30652458open access10.5546/aap.2019.e591668-3501https://doi.org/10.5546/aap.2019.e59