Alexander, Stephen PhChristopoulos, ArthurDavenport, Anthony PKelly, EamonnMathie, AlistairPeters, John AVeale, Emma LArmstrong, Jane FFaccenda, ElenaHarding, Simon DPawson, Adam JSouthan, ChristopherDavies, Jamie AAbbracchio, Maria PiaAlexander, WayneAl-Hosaini, KhaledBäck, MagnusBarnes, Nicholas MBathgate, RossBeaulieu, Jean-MartinBernstein, Kenneth EBettler, BernhardBirdsall, Nigel J MBlaho, VictoriaBoulay, FrancoisBousquet, CorinneBräuner-Osborne, HansBurnstock, GeoffreyCaló, GirolamoCastaño, Justo PCatt, Kevin JCeruti, StefaniaChazot, PaulChiang, NanChini, BiceChun, JeroldCianciulli, AntoniaCivelli, OlivierClapp, Lucie HCouture, RéjeanCsaba, ZsoltDahlgren, ClaesDent, GordonSingh, Khuraijam DhanachandraDouglas, Steven DDournaud, PascalEguchi, SatoruEscher, EmanuelFilardo, Edward JFong, TungFumagalli, MartaGainetdinov, Raul RGasparo, Marc deGerard, CraigGershengorn, MarvinGobeil, FernandGoodfriend, Theodore LGoudet, CyrilGregory, Karen JGundlach, Andrew LHamann, JörgHanson, JulienHauger, Richard LHay, Debbie LHeinemann, AkosHollenberg, Morley DHolliday, Nicholas DHoriuchi, MastguguHoyer, DanielHunyady, LászlóHusain, AhsanIJzerman, Adriaan PInagami, TadashiJacobson, Kenneth AJensen, Robert TJockers, RalfJonnalagadda, DeepaKarnik, SadashivaKaupmann, KlemensKemp, JacquelineKennedy, CharlesKihara, YasuyukiKitazawa, TakioKozielewicz, PawelKreienkamp, Hans-JürgenKukkonen, Jyrki PLangenhan, TobiasLeach, KatieLecca, DavideLee, John DLeeman, Susan ELeprince, JérômeLi, Xaria XWilliams, Tom LloydLolait, Stephen JLupp, AmelieMacrae, RobynMaguire, JanetMazella, JeanMcArdle, Craig AMelmed, ShlomoMichel, Martin CMiller, Laurence JMitolo, VincenzoMouillac, BernardMüller, Christa EMurphy, PhilipNahon, Jean-LouisNgo, TonyNorel, XavierNyimanu, DuuameneO'Carroll, Anne-MarieOffermanns, StefanPanaro, Maria AntoniettaParmentier, MarcPertwee, Roger GPin, Jean-PhilippeProssnitz, Eric RQuinn, MarkRamachandran, RithwikRay, ManishaReinscheid, Rainer KRondard, PhilippeRovati, G EnricoRuzza, ChiaraSanger, Gareth JSchöneberg, TorstenSchulte, GunnarSchulz, StefanSegaloff, Deborah LSerhan, Charles NStoddart, Leigh ASugimoto, YukihikoSummers, RogerTan, Valerie PThal, DavidThomas, Walter WallyTimmermans, Pieter B M W MTirupula, KalyanTulipano, GiovanniUnal, HamiyetUnger, ThomasValant, CelineVanderheyden, PatrickVaudry, DavidVaudry, HubertVilardaga, Jean-PierreWalker, Christopher SWang, Ji MingWard, Donald TWester, Hans-JürgenWillars, Gary BWoodruff, Trent MYao, ChengcanYe, Richard D2025-01-072025-01-072021https://hdl.handle.net/10668/25043The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15538. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Databases, PharmaceuticalHumansIon ChannelsLigandsPharmacologyReceptors, Cytoplasmic and NuclearReceptors, G-Protein-Coupledresearch article34529832open access10.1111/bph.155381476-5381https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bph.15538