García-Cabrera, EmilioJiménez-Mejías, Manuel E.Gil-Navarro, María VictoriaGómez-Gómez, M JOrtiz-Leyba, CCordero, ElisaPachón, J2025-01-272025-01-272010-05-16García-Cabrera E, Jiménez-Mejías ME, Gil Navarro MV, Gómez-Gómez MJ, Ortiz-Leyba C, Cordero E, et al Superinfection during treatment of nosocomial infections with tigecycline. Eur J Clin Microbiol Infect Dis. 2010 Jul;29(7):867-70812732-5326https://hdl.handle.net/10668/28450We performed a retrospective and observational study of 51 patients treated with tigecycline, as the treatment for nosocomial infections due to multidrug-resistant microorganisms, to evaluate the superinfection rate and their etiologies. Superinfections were diagnosed in 12 (23.5%) patients (seven due to Pseudomonas aeruginosa, 13.7%) and one patient had P. aeruginosa colonization. Five patients with superinfection died (41.6%), three due to superinfections and two to underlying diseases. The superinfection rate observed during tigecycline treatment is higher than that previously reported. Pseudomonas aeruginosa is the most frequent agent, being the cause of 58.5% of all superinfections.enMinimum Inhibitory ConcentrationNosocomial InfectionTigecyclineAcinetobacter BaumanniiStenotrophomonas MaltophiliaSuperinfectionTigecyclineNosocomial InfectionsMultidrug-Resistant OrganismsPseudomonas aeruginosaresearch article20473700restricted accessSobreinfecciónTigeciclinaInfecciones NosocomialesOrganismos Multirresistentes a MedicamentosPseudomonas aeruginosa10.1007/s10096-010-0942-y