Cobo, Fernando2014-02-242014-02-242013-09Cobo F. Application of maldi-tof mass spectrometry in clinical virology: a review. Open Virol J. 2013; 7:84-90http://hdl.handle.net/10668/1518Journal Article;MALDI-TOF mass spectrometry is a diagnostic tool of microbial identification and characterization based on the detection of the mass of molecules. In the majority of clinical laboratories, this technology is currently being used mainly for bacterial diagnosis, but several approaches in the field of virology have been investigated. The introduction of this technology in clinical virology will improve the diagnosis of infections produced by viruses but also the discovery of mutations and variants of these microorganisms as well as the detection of antiviral resistance. This review is focused on the main current applications of MALDI-TOF MS techniques in clinical virology showing the state of the art with respect to this exciting new technology.enMALDI-TOFMass spectrometryViral diagnosisGenotypingEspectrometría de MasasTécnicas de GenotipajeGenotipoVirologíaMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Mass SpectrometryMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Genotyping TechniquesMedical Subject Headings::Phenomena and Processes::Genetic Phenomena::GenotypeMedical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Microbiology::Virologyresearch article24222805open access10.2174/18743579201309270031874-3579PMC3821086