Miró, ÒscarMartínez, GemmaMasip, JosepGil, VíctorMartín-Sánchez, Francisco JavierLlorens, PereHerrero-Puente, PabloSánchez, CarolinaRichard, FernandoLucas-Invernón, JavierGarrido, José ManuelMebazaa, AlexandreRíos, JoséPeacock, W FrankHollander, Judd EJacob, JavierICA-SEMES Research Group Researchers2023-01-252023-01-252018-03-21http://hdl.handle.net/10668/12270To assess the effects of non-invasive ventilation (NIV) in emergency department (ED) patients with acute heart failure (AHF) on short term outcomes. Patients from the EAHFE Registry (a multicenter, observational, multipurpose, cohort-designed database including consecutive AHF patients in 41 Spanish EDs) were grouped based on NIV treatment (NIV+ and NIV-groups). Using propensity score (PS) methodology, we identified two subgroups of patients matched by 38 covariates and compared regarding 30-day survival (primary outcome). Interaction was investigated for age, sex, ischemic cardiomyopathy, chronic obstructive pulmonary disease, AHF precipitated by an acute coronary syndrome (ACS), AHF classified as hypertensive or acute pulmonary edema (APE), and systolic blood pressure (SBP). Secondary outcomes were intensive care unit (ICU) admission; mechanical ventilation; in-hospital, 3-day and 7-day mortality; and prolonged hospitalization (>7 days). Of 11,152 patients from the EAHFE (age (SD): 80 (10) years; 55.5% women), 718 (6.4%) were NIV+ and had a higher 30-day mortality (HR = 2.229; 95%CI = 1.861-2.670) (p 85 years, p  The use of NIV to treat AHF in ED is not associated with improved mortality outcomes and should be cautious in old patients and those with ACS and hypotension.enAcute heart failureEmergency departmentHeart failureNon-invasive ventilationOutcomeAcute Coronary SyndromeAcute DiseaseAgedAged, 80 and overCohort StudiesEmergency Service, HospitalFemaleHeart FailureHospital MortalityHumansIntensive Care UnitsLogistic ModelsMaleNoninvasive VentilationPropensity ScorePulmonary Disease, Chronic ObstructiveRegistriesRisk FactorsSpainTime FactorsTreatment Outcomeresearch article29572091open access10.1016/j.ejim.2018.03.0081879-0828https://zaguan.unizar.es/record/78761/files/texto_completo.pdf