Rodriguez-Peralvarez, ManuelDe la Mata, ManuelTsochatzis, Emmanuel2023-02-082023-02-082019-11-05Rodríguez-Perálvarez M, De la Mata M, Tsochatzis E. Tacrolimus Trough Concentrations After Liver Transplantation: Back to the Future. Transplantation. 2020 Apr;104(4):e114http://hdl.handle.net/10668/14890We read with great interest the retrospective study by Di Maira et al1 which failed to establish an association between early exposure to calcineurin inhibitors (CNIs) and long-term outcomes among 432 patients who underwent liver transplantation (LT) in 2 centers. The authors suggested that early minimization of CNIs may have a limited prognostic impact.enGraft rejectionImmunosuppressive agentsLiver transplantationTacrolimusTacrolimus Trough Concentrations After Liver Transplantation: Back to the Future.Research article31880755open accessInmunosupresoresRechazo de injertoTacrolimusTrasplante de hígado10.1097/TP.00000000000030861534-6080https://journals.lww.com/transplantjournal/Fulltext/2020/04000/Tacrolimus_Trough_Concentrations_After_Liver.38.aspx