Vázquez-Alonso, FPuche-Sanz, ISánchez-Ramos, CFlores-Martín, JVicente-Prados, JCózar-Olmo, J M2013-03-072013-03-072012-08-22Vázquez-Alonso F, Puche-Sanz I, Sánchez-Ramos C, Flores-Martín J, Vicente-Prados J, Cózar-Olmo JM. Primary renal lymphoma: long-term results of two patients treated with a chemotherapy + rituximab protocol. Case Rep Oncol Med; 2012:726424http://hdl.handle.net/10668/807Journal Article;Primary renal lymphoma (PRL) is a rare disease of which the etiology and pathogenesis remain controversial, and there is currently no standard treatment for it. We present the results of a long-term followup of two patients who were diagnosed with PRL and treated with cyclophosphamide, adriamycin, vincristine, prednisolone and rituximab (CHOP + R) regimen. Both patients reached a complete response, and there is no evidence of recurrence after 4.5- and 5-year followup periods. Based on our experience and other recently published studies, we recommend the combination of CHOP + rituximab as the elective treatment for this disease. To our knowledge, this is the longest followup period with a complete response that has been reported with this modality of treatment.enLinfomaAntineoplastic AgentsrituximabAntineoplásicosAnticuerpos MonoclonalesCiclofosfamidaDoxorrubicinaVincristinaPrednisolonaR-CHOP protocolNeoplasias RenalesMedical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::LymphomaMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, MonoclonalMedical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic AgentsMedical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Halogenated::Mustard Compounds::Nitrogen Mustard Compounds::Phosphoramide Mustards::CyclophosphamideMedical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Polycyclic Hydrocarbons, Aromatic::Naphthacenes::Anthracyclines::Daunorubicin::DoxorubicinMedical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Alkaloids::Indole Alkaloids::Secologanin Tryptamine Alkaloids::Vinca Alkaloids::VincristineMedical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Steroids::Pregnanes::Pregnadienes::Pregnadienetriols::PrednisoloneMedical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Urologic Neoplasms::Kidney NeoplasmsPrimary renal lymphoma: long-term results of two patients treated with a chemotherapy + rituximab protocol.research article22997596open access10.1155/2012/7264242090-6714PMC3446643