Salguero, JosebaGomez-Gomez, EnriqueValero-Rosa, JoseCarrasco-Valiente, JuliaMesa, JuanMartin, CristinaCampos-Hernandez, Juan PabloRubio, Juan ManuelLopez, DanielRequena, Maria Jose2023-02-092023-02-092020-09-21Salguero J, Gómez-Gómez E, Valero-Rosa J, Carrasco-Valiente J, Mesa J, Martin C, et al. Role of Multiparametric Prostate Magnetic Resonance Imaging before Confirmatory Biopsy in Assessing the Risk of Prostate Cancer Progression during Active Surveillance. Korean J Radiol. 2021 Apr;22(4):559-567http://hdl.handle.net/10668/16752To evaluate the impact of multiparametric magnetic resonance imaging (mpMRI) before confirmatory prostate biopsy in patients under active surveillance (AS). This retrospective study included 170 patients with Gleason grade 6 prostate cancer initially enrolled in an AS program between 2011 and 2019. Prostate mpMRI was performed using a 1.5 tesla (T) magnetic resonance imaging system with a 16-channel phased-array body coil. The protocol included T1-weighted, T2-weighted, diffusion-weighted, and dynamic contrast-enhanced imaging sequences. Uroradiology reports generated by a specialist were based on prostate imaging-reporting and data system (PI-RADS) version 2. Univariate and multivariate analyses were performed based on regression models. The reclassification rate at confirmatory biopsy was higher in patients with suspicious lesions on mpMRI (PI-RADS score ≥ 3) (n = 47) than in patients with non-suspicious mpMRIs (n = 61) and who did not undergo mpMRIs (n = 62) (66%, 26.2%, and 24.2%, respectively; p Inclusion of mpMRI before the confirmatory biopsy is useful to stratify the risk of reclassification during the biopsy as well as to evaluate the risk of progression to active treatment during follow-up.enAttribution-Noncommercial 4.0 Internationalhttps://creativecommons.org/licenses/by-nc/4.0/Active surveillanceActive treatmentConfirmatory biopsy reclassificationMultiparametric prostate magnetic resonance imagingProgression riskProstate cancerAgedDisease progressionHumansLogistic modelsMaleMiddle agedMultiparametric magnetic resonance imagingNeoplasm gradingProgression-free survivalProstate-specific antigenProstatic neoplasmsRetrospective studiesRiskResearch article33289358open accessAntígeno prostático específicoClasificación del tumorEstudios retrospectivosImágenes de resonancia magnéticaNeoplasias de la próstataPersona de mediana edadProgresión de la EnfermedadRiesgo10.3348/kjr.2020.08522005-8330PMC8005352https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005352https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005352/pdf