Dréno, BrigitteCerio, RinoDirschka, ThomasNart, Ignasi FiguerasLear, John TPeris, Kettyde Casas, Andrés RuizKaleci, ShanikoPellacani, Giovanni2023-01-252023-01-252017http://hdl.handle.net/10668/11226Actinic keratosis (AK) lesions are surrounded by field cancerization (areas of subclinical, non-visible sun damage). Existing AK grading tools rely on AK counts, which are not reproducible. An Actinic Keratosis Field Assessment Scale (AK-FAS) for grading the severity of AK/field was developed. Standardized photographs of patients representing the full range of AK severity were collected. Six investigators independently rated each photograph according to 3 criteria: AK area (total skin area affected by AK lesions), hyperkeratosis and sun damage. Inter-rater reproducibility was good for all 3 criteria. Validation of the AK-FAS showed good reproducibility for AK area and hyperkeratosis, even for dermatologists untrained on use of the scale. In conclusion, the AK-FAS is objective, easy to use and implement, and reproducible. It incorporates assessment of the entire field affected by AK instead of relying on lesion counts. Use of the AK-FAS may standardize AK diagnosis, making it relevant to routine clinical practice.enAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/FaceHumansKeratosisKeratosis, ActinicPhotographyReproducibility of ResultsScalpSeverity of Illness IndexSunlightresearch article28536731open access10.2340/00015555-27101651-2057https://www.medicaljournals.se/acta/download/10.2340/00015555-2710/