Sevilla García, María IsabelRueda Domínguez, AntonioAlba Conejo, Emilio2013-01-142013-01-141999-04-07Sevilla Garcia I, Rueda A, Alba E. Irinotecan-induced central nervous system toxicity: a case report. J. Natl. Cancer Inst.. 1999; 91(7):6470027-8874http://hdl.handle.net/10668/738Here we describe the first case, to our knowledge, of CNS [Central nervous system] toxicity in a patient treated with irinotecan.enIrinotecanCamptotecinaInfusiones IntravenosasAntineoplásicos FitogénicosMedical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Alkaloids::CamptothecinCentral Nervous SystemMedical Subject Headings::Check Tags::FemaleMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Administration Routes::Infusions, Parenteral::Infusions, IntravenousMedical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle AgedMedical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents::Antineoplastic Agents, Phytogenicletter10203287open access10.1093/jnci/91.7.6471460-2105