Comments on: Differential IgG4-Producing Plasma Cell Infiltration in Non- and Post-Transplant Plasma Cell Hepatitis.

Aguilera, IsabelSousa, Jose Manuel2023-05-032023-05-032022-08-05Aguilera I, Sousa JM. Comments on: Differential IgG4-Producing Plasma Cell Infiltration in Non- and Post-Transplant Plasma Cell Hepatitis. Transpl Int. 2022 Aug 5;35:10590.http://hdl.handle.net/10668/20756We read with interest the article by Horwich et al. about IgG4-producing plasma cells. The aim of the study was to use IgG4-positivity as a differential biomarker for distinct clinical presentations of plasma cell hepatitis before and after liver transplantation. They found a high degree of IgG4-PC infiltration more frequently associated with plasma cell rejection (PCR) than other types of AIH and concluded that IgG4-positivity might serve as a valuable diagnostic tool in the post-LT setting.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/GSTT1IgG4PC-rich Rliver transplantplasma cellsHepatitisHumansImmunoglobulin GInflammationLiver TransplantationPlasma CellsTransplantsComments on: Differential IgG4-Producing Plasma Cell Infiltration in Non- and Post-Transplant Plasma Cell Hepatitis.research article35992745open accessInmunoglobulina GCélulas plasmáticasInseminación artificial homólogaTrasplante de hígadoBiomarcadoresHepatitisReacción en cadena de la polimerasa10.3389/ti.2022.105901432-2277PMC9389647https://www.frontierspartnerships.org/articles/10.3389/ti.2022.10590/pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389647/pdf