Balaña, CAlonso, MHernandez-Lain, AHernandez, APerez-Segura, PPineda, ERamos, ASanchez, A RTeixidor, PVerger, EBenavides, M2023-01-252023-01-252017-10-20Balañá C, Alonso M, Hernandez-Lain A, Hernandez A, Perez-Segura P, Pineda E, et al. SEOM clinical guidelines for anaplastic gliomas (2017). Clin Transl Oncol. 2018 Jan;20(1):16-21. doi: 10.1007/s12094-017-1762-7. Epub 2017 Oct 20. Erratum in: Clin Transl Oncol. 2018 Jul;20(7):937http://hdl.handle.net/10668/11715The SEOM/GEINO clinical guidelines provide recommendations for radiological, and molecular diagnosis, treatment and follow-up of adult patients with anaplastic gliomas (AG). We followed the 2016 WHO classification which specifies the major diagnostic/prognostic and predictive value of IDH1/IDH2 missense mutations and 1p/19q codeletions in AG. The diagnosis of anaplastic oligoastrocytoma is discouraged. Surgery, radiotherapy and chemotherapy with PCV or TMZ are the first-line standard of care for AG with slight modifications according to molecular variables. A multidisciplinary team is highly recommended in the management of these tumors.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Anaplastic astrocytomaAnaplastic gliomaAnaplastic oligodendrogliomaBrain NeoplasmsGliomaHumansresearch article29058264open accessNeoplasias encefálicasOligodendrogliomaHumanos10.1007/s12094-017-1762-71699-3055PMC5785606https://link.springer.com/content/pdf/10.1007/s12094-017-1762-7.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785606/pdf