Bernabeu-Wittel, JLuque, RCorbi, RMantrana-Bermejo, MNavarrete, MVallejo, ABernabeu-Wittel, M2015-01-202015-01-202010Bernabeu-Wittel J, Luque R, Corbi R, Mantrana-Bermejo M, Navarrete M, Vallejo A, et al. Bacillary angiomatosis with atypical clinical presentation in an immunocompetent patient. Indian J Dermatol Venereol Leprol. 2010; 76(6):682-50378-6323http://hdl.handle.net/10668/1792Case Reports; Journal Article;Bacillary angiomatosis is a recently described infectious disease that usually affects immunosupressed hosts with a previous history of contact with cats. We report a rare case of bacillary angiomatosis in an immunocompetent 59-year-old woman with no history of previous exposure to cats, and atypical clinical features (fever and subcutaneous nodules with ulceration on the left ankle). Histopathology of the lesion showed extensive ulceration and reactive tumor-like vascular proliferation of the blood vessels with swollen endothelial cells and an inflammatory infiltrate including neutrophils and lymphocytes in the dermis and subcutis. Staining with the Warthin-Starry method demonstrated the presence of clustered bacilli located in the extracellular matrix adjacent to the proliferating endothelial cells. Diagnosis was confirmed with the detection of Bartonella spp. DNA in the affected skin and in bone marrow using polymerase chain reaction.enBartonella quintanaBartonella henselaeImmunocompetentInfecciones por BartonellaProliferación de la CélulaDiagnóstico DiferencialDoxiciclinaEndotelio VascularHuésped InmunocomprometidoAngiomatosis BacilarMedical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Bartonellaceae InfectionsMedical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell ProliferationMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnosis, DifferentialMedical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Polycyclic Hydrocarbons, Aromatic::Naphthacenes::Tetracyclines::DoxycyclineMedical Subject Headings::Anatomy::Tissues::Epithelium::Endothelium::Endothelium, VascularMedical Subject Headings::Check Tags::FemaleMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immunocompromised HostMedical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle AgedMedical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Skin Diseases, Bacterial::Angiomatosis, Bacillaryresearch article21079313open access10.4103/0378-6323.724690973-3922