Ramos-Rincon, Jose-ManuelBernabeu-Wittel, MaximoFiteni-Mera, IsabelLopez-Sampalo, AlmudenaLopez-Rios, CarmenGarcia-Andreu, Maria-Del-MarMancebo-Sevilla, Juan-JoseJimenez-Juan, CarlosMatia-Sanz, MartaLopez-Quirantes, PabloRubio-Rivas, ManuelParedes-Ruiz, DianaGonzalez-San-Narciso, CandelaGonzalez-Vega, RocíoSanz-Espinosa, PabloHernandez-Milian, AlmudenaGonzalez-Noya, AmaraGil-Sanchez, RicardoBoixeda, RamonAlcala-Pedrajas, Jose-NicolasPalop-Cervera, MartaCortes-Rodriguez, BegoñaGuisado-Espartero, Maria-EstherMella-Perez, CarmenGómez-Huelgas, RicardoSEMI-COVID-19 Network2023-05-032023-05-032021-10-03Ramos-Rincón JM, Bernabeu-Wittel M, Fiteni-Mera I, López-Sampalo A, López-Ríos C, García-Andreu MD, et al.; SEMI-COVID-19 Network. Clinical features and risk factors for mortality among long-term care facility residents hospitalized due to COVID-19 in Spain. J Gerontol A Biol Sci Med Sci. 2022 Apr 1;77(4)http://hdl.handle.net/10668/19783COVID-19 severely impacted older adults and long-term care facility (LTCF) residents. Our primary aim was to describe differences in clinical and epidemiological variables, in-hospital management, and outcomes between LTCF residents and community-dwelling older adults hospitalized with COVID-19. The secondary aim was to identify risk factors for mortality due to COVID-19 in hospitalized LTCF residents. This is a cross-sectional analysis within a retrospective cohort of hospitalized patients ≥75 years with confirmed COVID-19 admitted to 160 Spanish hospitals. Differences between groups and factors associated with mortality among LTCF residents were assessed through comparisons and logistic regression analysis. Of 6 189 patients ≥75 years, 1 185 (19.1%) were LTCF residents and 4 548 (73.5%) were community-dwelling. LTCF residents were older (median: 87.4 vs 82.1 years), mostly female (61.6% vs 43.2%), had more severe functional dependence (47.0% vs 7.8%), more comorbidities (Charlson Comorbidity Index: 6 vs 5), had dementia more often (59.1% vs 14.4%), and had shorter duration of symptoms (median: 3 vs 6 days) than community-dwelling patients (all, p Basal functional status and COVID-19 severity are risk factors of mortality in LTCF residents. The lower adjusted mortality rate in LTCF residents may be explained by earlier identification, treatment, and hospitalization for COVID-19.enCOVID-19EpidemiologyMortalityNursing homesRisk factorsAgedCOVID-19Cross-Sectional StudiesFemaleHospitalizationHumansLong-Term CareMaleRetrospective StudiesRisk FactorsSpainresearch article34626477open accessNursing HomesRisk Factorsepidemiologymortality10.1093/gerona/glab3051758-535Xhttps://academic.oup.com/biomedgerontology/article-pdf/77/4/e138/43230458/glab305.pdf