Fernández-Pérez, G COñate Miranda, MFernández-Rodríguez, PVelasco Casares, MCorral de la Calle, MFranco López, ÁDíez Blanco, MCuchat, J M Oñate2023-02-092023-02-092020-11-17http://hdl.handle.net/10668/16781COVID-19 is a disease with many clinical, biochemical, and radiological signs that has a predilection for the lungs, probably because of the high number of ACE-2 receptors in this organ. The infection of cells activates proinflammatory substances, causing diffuse alveolar damage, which is the histopathological basis of ARDS. The exudative phase would manifest as ground-glass opacities and consolidation, and the proliferative phase would manifest as a tendency toward a more linear morphology. Both CT and PET/CT findings support the inflammatory character of the lung lesions in the initial phase of the disease and in patients with mild-moderate disease. Severe cases have pulmonary hypoperfusion that is likely due to abnormal alveolar ventilation and perfusion. On the other hand, a prothrombotic state increases the risk of thromboembolic disease through the activation of coagulation and platelet pathways with the production of fibrin degradation products (D-dimer) and consumption of platelets.enCOVID-19PET/TCPercusión pulmonar PBVSARS-2SARS-CoV-2TC alta resoluciónTC doble energíadual-energy CThigh-resolution CTlung perfusion blood volumeAgedCOVID-19FemaleHumansMaleMiddle AgedPositron Emission Tomography Computed TomographyTomography, X-Ray Computedresearch article33309398open access10.1016/j.rx.2020.10.0062173-5107PMC7671642https://doi.org/10.1016/j.rx.2020.10.006https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671642/pdf