RT Conference Proceedings T1 An ex vivo native environment precision medicine test shows high clinical correlation with responses to first line acute myeloid leukemia treatment A1 Montesinos, P A1 Ballesteros, J A1 Martinez Cuadron, D A1 Martinez Lopez, J A1 Serrano, J A1 Perez de Oteyza, J A1 Fernandez, P A1 Rodriguez Macias, G A1 Vidriales, B A1 Herrera, P A1 Tormo, M A1 Bergua, J A1 Garcia, R A1 Vives, S A1 Fernandez, MA A1 Lavilla, E A1 Jimenez, S A1 Perez Simon, JA A1 Simiele, A A1 Gonzalez, A A1 Gonzalez, B A1 Burgaleta, C A1 Lopez, JA A1 Bethancourt, C A1 Bautista, G A1 Alonso, A A1 Colorado, M A1 Sierra, J A1 Navas, B A1 Hernandez Rivas, JA A1 Vera, JA A1 Amador, L A1 Cordoba, R A1 de la Fuente, A A1 Ramos, F A1 Cervero, CJ A1 Rayon, C A1 Salamero, O A1 Marti, E A1 Loez, A A1 Olave, T A1 Gaspar, M A1 Gorrochategui, J A1 Rojas, JL A1 Gomez, C A1 Hernandez, P A1 Robles, A A1 Ortega, I A1 Villoria, J A1 Moscardo, F A1 Troconiz, I A1 Sanz, MA K1 Adulto K1 Médula ósea K1 Citarabina K1 Ambiente K1 Humanos K1 Idarrubicina K1 Quimioterapia de inducción K1 Mantenimiento AB This novel test is able to predict the clinical response to Ida+Ara-C induction with overall correlation and predictive values of 80%, higher than ever achieved. Considering this result and current clinical responserate of 66.7% (70% in this study), clear clinical benefits can be achieved withthe use of the test. Adding the cytogenetic risk profile further increase the correlationto 90%. Thus this novel test may be valuable information to guide 1st line patient therapy PB Ferrata Storti Foundation SN 0390-6078 YR 2016 FD 2016-06 LK http://hdl.handle.net/10668/2442 UL http://hdl.handle.net/10668/2442 LA en NO Montesinos P, Ballesteros J, Martinez Cuadron D. Martinez Lopez J, Serrano J, Perez de Oteyza J et al. An ex vivo native environment precision medicine test shows high clinical correlation with responses to first line acute myeloid leukemia treatment. Haematologica. 2016; 101 (s1) P569 DS RISalud RD Apr 6, 2025