RT Journal Article
T1 Efficacy of low-intensity psychological intervention applied by ICTs for the treatment of depression in primary care: a controlled trial.
A1 Castro, Adoración
A1 García-Palacios, Azucena
A1 García-Campayo, Javier
A1 Mayoral, Fermín
A1 Botella, Cristina
A1 García-Herrera, José María
A1 Pérez-Yus, Mari-Cruz
A1 Vives, Margalida
A1 Baños, Rosa M
A1 Roca, Miquel
A1 Gili, Margalida
K1 Depression
K1 Primary health care
K1 Computer-delivered psychotherapy
K1 Randomized controlled trial
K1 Protocolos clínicos
K1 Depresión
K1 Promoción de la salud
K1 Atención plena
K1 Atención primaria de la salud
K1 Psicoterapia
K1 Tratamiento asistido por ordenador
AB BACKGROUNDDepression is one of the most common disorders in Psychiatric and Primary Care settings and is associated with significant disability and economic costs. Low-intensity psychological interventions applied by Information and Communication Technologies (ICTs) could be an efficacious and cost-effective therapeutic option for the treatment of depression. The aim of this study is to assess 3 low-intensity psychological interventions applied by ICTs (healthy lifestyle, positive affect and mindfulness) in Primary Care; significant efficacy for depression treatment has previously showed in specialized clinical settings by those interventions, but ICTs were not used.METHODMulticenter controlled randomized clinical trial in 4 parallel groups. Interventions have been designed and on-line device adaptation has been carried out. Subsequently, the randomized controlled clinical trial will be conducted. A sample of N = 240 mild and moderate depressed patients will be recruited and assessed in Primary Care settings. Patients will be randomly assigned to a) healthy lifestyle psychoeducational program + improved primary care usual treatment (ITAU), b) focused program on positive affect promotion + ITAU c) mindfulness + ITAU or d) ITAU. The intervention format will be one face to face session and four ICTs on-line modules. Patients will be diagnosed with MINI psychiatric interview. Main outcome will be PHQ-9 score. They will be also assessed by SF-12 Health Survey, Client Service Receipt Inventory, EuroQoL-5D questionnaire, Positive and Negative Affect Scale, Five Facet Mindfulness Questionnaire and the Pemberton Happiness Index. Patients will be assessed at baseline, post, 6 and 12 post-treatment months. An intention to treat and per protocol analysis will be performed.DISCUSSIONLow-intensity psychological interventions applied by Information and Communication Technologies have been not used before in Spain and could be an efficacious and cost-effective therapeutic option for depression treatment. The strength of the study is that it is the first multicenter controlled randomized clinical trial of three low intensity and self-guided interventions applied by ICTs (healthy lifestyle psychoeducational program; focused program on positive affect promotion and brief intervention based on mindfulness) in Primary Care settings.TRIAL REGISTRATIONCurrent Controlled Trials ISRCTN82388279 . Registered 16 April 2014.
PB Biomed Central
YR 2015
FD 2015-05-07
LK http://hdl.handle.net/10668/2343
UL http://hdl.handle.net/10668/2343
LA en
NO Castro A, García-Palacios A, García-Campayo J, Mayoral F, Botella C, García-Herrera JM, et al. Efficacy of low-intensity psychological intervention applied by ICTs for the treatment of depression in primary care: a controlled trial. BMC Psychiatry. 2015; 15:106
NO Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 10, 2025