TY  - JOUR
AU  - Malhotra, Sunny
AU  - Costa, Carme
AU  - Eixarch, Herena
AU  - Keller, Christian W
AU  - Amman, Lukas
AU  - Martínez-Banaclocha, Helios
AU  - Midaglia, Luciana
AU  - Sarró, Eduard
AU  - Machín-Díaz, Isabel
AU  - Villar, Luisa M
AU  - Triviño, Juan Carlos
AU  - Oliver-Martos, Begoña
AU  - Parladé, Laura Navarro
AU  - Calvo-Barreiro, Laura
AU  - Matesanz, Fuencisla
AU  - Vandenbroeck, Koen
AU  - Urcelay, Elena
AU  - Martínez-Ginés, María-Luisa
AU  - Tejeda-Velarde, Amalia
AU  - Fissolo, Nicolás
AU  - Castilló, Joaquín
AU  - Sanchez, Alex
AU  - Robertson, Avril A B
AU  - Clemente, Diego
AU  - Prinz, Marco
AU  - Pelegrin, Pablo
AU  - Lünemann, Jan D
AU  - Espejo, Carmen
AU  - Montalban, Xavier
AU  - Comabella, Manuel
PY  - 2020
DO  - 10.1093/brain/awaa084
UR  - http://hdl.handle.net/10668/15363
T2  - Brain : a journal of neurology
AB  - Primary progressive multiple sclerosis is a poorly understood disease entity with no specific prognostic biomarkers and scarce therapeutic options. We aimed to identify disease activity biomarkers in multiple sclerosis by performing an RNA sequencing...
LA  - en
KW  - NLRP3 inflammasome
KW  - biomarkers
KW  - multiple sclerosis
KW  - prognostic factor
KW  - therapeutic target
KW  - Adult
KW  - Animals
KW  - Biomarkers
KW  - Encephalomyelitis, Autoimmune, Experimental
KW  - Female
KW  - Humans
KW  - Inflammasomes
KW  - Interleukin-1beta
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Multiple Sclerosis, Chronic Progressive
KW  - NLR Family, Pyrin Domain-Containing 3 Protein
KW  - Prognosis
TI  - NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients.
TY  - research article
VL  - 143
ER  -