RT Journal Article
T1 Age-Related Macular Degeneration: Clinical Findings following Treatment with Antiangiogenic Drugs.
A1 Casaroli-Marano, Ricardo
A1 Gallego-Pinazo, Roberto
A1 Torrón Fernández-Blanco, Clemencia
A1 Figueroa, Marta S
A1 Pina Marín, Begoña
A1 Fernández-Baca Vaca, Gustavo
A1 Piñero-Bustamante, Antonio
A1 Donate López, Juan
A1 García-Arumí, José
A1 Farrés Martí, Jordi
K1 Degeneración macular
K1 España
K1 Estudios multicéntricos como asunto
K1 Estudios retrospectivos
K1 Agudeza visual
K1 Demografía
AB Purpose. To survey the management of patients with neovascular age-related macular degeneration (nvAMD) in Spain. Methods. An observational retrospective multicenter study was conducted. The variables analyzed were sociodemographic characteristics, foveal and macular thickness, visual acuity (VA), type of treatment, number of injections, and the initial administration of a loading dose of an antiangiogenic drug. Results. 208 patients were followed up during 23.4 months in average. During the first and second years, patients received a mean of 4.5 ± 1.8 and 1.6 ± 2.1 injections of antiangiogenic drugs, and 5.4 ± 2.8 and 3.6 ± 2.2 follow-up visits were performed, respectively. The highest improvement in VA was observed at 3 months of follow-up, followed by a decrease in the response that stabilized above baseline values until the end of the study. Patients who received an initial loading dose presented greater VA gains than those without. Conclusions. Our results suggest the need for a more standardized approach in the management and diagnosis of nvAMD receiving VEGF inhibitors. To achieve the visual outcomes reported in pivotal trials, an early diagnosis, proactive approach (more treating than follow-up visits), and a close monitoring might be the key to successfully manage nvAMD.
PB Hindawi Publishing Corporation
SN 2090-004X
YR 2014
FD 2014-02-16
LK http://hdl.handle.net/10668/1612
UL http://hdl.handle.net/10668/1612
LA en
NO Casaroli-Marano R, Gallego-Pinazo R, Fernández-Blanco CT, Figueroa MS, Pina Marín B, Fernández-Baca Vaca G, et al. Age-Related Macular Degeneration: Clinical Findings following Treatment with Antiangiogenic Drugs. J Ophthalmol; 2014:346360
NO Journal Article;
DS RISalud
RD Aug 20, 2025