TY  - GEN
AU  - Martin, Francisco
AU  - Sanchez-Hernandez, Sabina
AU  - Gutierrez-Guerrero, Alejandra
AU  - Pinedo-Gomez, Javier
AU  - Benabdellah, Karim
PY  - 2016
DO  - 10.3390/ijms17091507
SN  - 1422-0067
UR  - http://hdl.handle.net/10668/19271
T2  - International journal of molecular sciences
AB  - The clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 9 endonuclease (Cas9) derived from bacterial adaptive immune systems is a revolutionary tool used in both basic and applied science. It is a versatile system that...
LA  - en
PB  - Mdpi
KW  - specific nucleases
KW  - CRISPR
KW  - cas9
KW  - off-target sites
KW  - real target cells
KW  - unbiased
KW  - biased
KW  - CHIPSeq
KW  - IDLVs
KW  - GUIDE-seq
KW  - LAM-HTGTS
KW  - Genome-wide analysis
KW  - Chip-seq
KW  - Crispr-cas9
KW  - Cas9
KW  - Repeats
KW  - Sites
KW  - Mutations
KW  - Nucleases
KW  - Talens
KW  - Genes
TI  - Biased and Unbiased Methods for the Detection of Off-Target Cleavage by CRISPR/Cas9: An Overview
TY  - review
VL  - 17
ER  -