TY - GEN AU - Espejo-Cruz, Maria Lola AU - Gonzalez-Rubio, Sandra AU - Zamora-Olaya, Javier AU - Amado-Torres, Victor AU - Alejandre, Rafael AU - Sanchez-Frias, Marina AU - Ciria, Ruben AU - De la Mata, Manuel AU - Rodriguez-Peralvarez, Manuel AU - Ferrin, Gustavo PY - 2021 DO - 10.3390/ijms222313073 UR - https://hdl.handle.net/10668/25892 T2 - International journal of molecular sciences AB - Hepatocellular carcinoma (HCC) is the fifth most common neoplasm and a major cause of cancer-related death worldwide. There is no ideal biomarker allowing early diagnosis of HCC and tumor surveillance in patients receiving therapy. Liquid biopsy, and... LA - en PB - Mdpi KW - hepatocellular carcinoma KW - liquid biopsy KW - circulating tumor cells KW - dynamic changes KW - therapeutic target KW - Cancer stem-cells KW - Mesenchymal transition KW - Liver-transplantation KW - Microvascular invasion KW - Clinical-significance KW - Peripheral-blood KW - Early recurrence KW - Liquid biopsy KW - Metastasis KW - Epcam TI - Circulating Tumor Cells in Hepatocellular Carcinoma: A Comprehensive Review and Critical Appraisal TY - review VL - 22 ER -