TY - JOUR AU - Bejarano-García, José Antonio AU - Millán-Uclés, África AU - Rosado, Iván V AU - Sánchez-Abarca, Luís Ignacio AU - Caballero-Velázquez, Teresa AU - Durán-Galván, María José AU - Pérez-Simón, José Antonio AU - Piruat, José I PY - 2016 DO - 10.1038/cddis.2016.411 UR - http://hdl.handle.net/10668/10665 T2 - Cell death & disease AB - It is established that hematopoietic stem cells (HSC) in the hypoxic bone marrow have adapted their metabolism to oxygen-limiting conditions. This adaptation includes suppression of mitochondrial activity, induction of anerobic glycolysis, and... LA - en KW - Animals KW - B-Lymphocytes KW - Bone Marrow KW - Cell Hypoxia KW - Cell Lineage KW - Cell Survival KW - Colony-Forming Units Assay KW - Electron Transport Complex II KW - Gene Deletion KW - Gene Expression Regulation KW - Hematopoietic Stem Cells KW - Leukocytes KW - Membrane Proteins KW - Mice KW - Mitochondria KW - RNA, Messenger KW - Spleen KW - Succinate Dehydrogenase KW - T-Lymphocytes KW - Thymus Gland TI - Sensitivity of hematopoietic stem cells to mitochondrial dysfunction by SdhD gene deletion. TY - research article VL - 7 ER -