TY - JOUR AU - Gahete, Manuel D AU - Del Rio-Moreno, Mercedes AU - Camargo, Antonio AU - Alcala-Diaz, Juan F AU - Alors-Perez, Emilia AU - Delgado-Lista, Javier AU - Reyes, Oscar AU - Ventura, Sebastian AU - Perez-Martinez, Pablo AU - CastaƱo, Justo P AU - Lopez-Miranda, Jose AU - Luque, Raul M PY - 2018 DO - 10.1016/j.ebiom.2018.10.056 UR - http://hdl.handle.net/10668/13196 T2 - EBioMedicine AB - Type-2 diabetes mellitus (T2DM) is a major health problem with increasing incidence, which severely impacts cardiovascular disease. Because T2DM is associated with altered gene expression and aberrant splicing, we hypothesized that dysregulations in... LA - en PB - The Lancet Publishing Group KW - OGTT KW - Peripheral blood mononuclear cells (PBMCs) KW - Postprandial state KW - RNUs KW - Spliceosome KW - Biomarkers KW - Cardiovascular Diseases KW - Diabetes Mellitus, Type 2 KW - Female KW - Glycated Hemoglobin KW - Humans KW - Leukocytes, Mononuclear KW - Male KW - Middle Aged KW - Predictive Value of Tests KW - RNA Splicing TI - Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study. TY - research article VL - 37 ER -