TY - JOUR AU - Hernández-Chirlaque, Cristina AU - Gámez-Belmonte, Reyes AU - Ocón, Borja AU - Martínez-Moya, Patricia AU - Wirtz, Stefan AU - Sánchez de Medina, Fermín AU - Martínez-Augustin, Olga PY - 2017 DO - 10.1093/ecco-jcc/jjw222 UR - http://hdl.handle.net/10668/10726 T2 - Journal of Crohn's & colitis AB - Two alkaline phosphatase isoforms, intestinal [IAP] and tissue non-specific alkaline phosphatase [TNAP], are coexpressed in mouse colon, with the latter predominating in colitis. We aimed to examine the role of TNAP in T lymphocytes, using... LA - en KW - Alkaline phosphatase KW - Rag1-/- KW - T cells KW - anti-CD3 KW - colitis KW - Alkaline Phosphatase KW - Animals KW - Cell Proliferation KW - Colitis KW - Cytokines KW - Enzyme Inhibitors KW - Gene Expression KW - Heterozygote KW - Homeodomain Proteins KW - Levamisole KW - Lymphocyte Activation KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Phenylalanine KW - Primary Cell Culture KW - RNA, Messenger KW - Spleen KW - T-Lymphocytes KW - Theophylline TI - Tissue Non-specific Alkaline Phosphatase Expression is Needed for the Full Stimulation of T Cells and T Cell-Dependent Colitis. TY - research article VL - 11 ER -