TY  - JOUR
AU  - Pacheco-Garcia, Juan Luis
AU  - Anoz-Carbonell, Ernesto
AU  - Vankova, Pavla
AU  - Kannan, Adithi
AU  - Palomino-Morales, Rogelio
AU  - Mesa-Torres, Noel
AU  - Salido, Eduardo
AU  - Man, Petr
AU  - Medina, Milagros
AU  - Naganathan, Athi N
AU  - Pey, Angel L
PY  - 2021
DO  - 10.1016/j.redox.2021.102112
UR  - https://hdl.handle.net/10668/27991
T2  - Redox biology
AB  - The multifunctional nature of human flavoproteins is critically linked to their ability to populate multiple conformational states. Ligand binding, post-translational modifications and disease-associated mutations can reshape this functional...
LA  - en
KW  - Disease-causing mutation
KW  - Flavoprotein
KW  - Ligand binding
KW  - Multifunctional protein
KW  - NQO1
KW  - Post-translational modification
KW  - Flavin-Adenine Dinucleotide
KW  - Humans
KW  - Mutation, Missense
KW  - NAD
KW  - NAD(P)H Dehydrogenase (Quinone)
KW  - Protein Binding
KW  - Quinones
TI  - Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue.
TY  - research article
VL  - 46
ER  -