TY  - JOUR
AU  - Tong, Hoi Y
AU  - Dávila-Fajardo, Cristina Lucía
AU  - Borobia, Alberto M
AU  - Martínez-González, Luis Javier
AU  - Lubomirov, Rubin
AU  - Perea León, Laura María
AU  - Blanco Bañares, María J
AU  - Díaz-Villamarín, Xando
AU  - Fernández-Capitán, Carmen
AU  - Cabeza Barrera, José
AU  - Carcas, Antonio J
PY  - 2016
DO  - 10.1371/journal.pone.0150456
UR  - http://hdl.handle.net/10668/2497
T2  - PloS One
AB  - There is a strong association between genetic polymorphisms and the acenocoumarol dosage requirements. Genotyping the polymorphisms involved in the pharmacokinetics and pharmacodynamics of acenocoumarol before starting anticoagulant therapy would...
LA  - en
PB  - Public Library of Science
KW  - Algoritmos
KW  - Anticoagulantes
KW  - Humanos
KW  - Farmacogenética
KW  - España
KW  - Acenocumarol
KW  - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged
KW  - Medical Subject Headings::Phenomena and Processes::Mathematical Concepts::Algorithms
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Hematologic Agents::Anticoagulants
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
KW  - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Pharmacology::Pharmacogenetics
KW  - Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Benzopyrans::Coumarins::4-Hydroxycoumarins::Acenocoumarol
TI  - A New Pharmacogenetic Algorithm to Predict the Most Appropriate Dosage of Acenocoumarol for Stable Anticoagulation in a Mixed Spanish Population.
TY  - research article
ER  -