RT Journal Article
T1 Spanish Pediatric Inflammatory Bowel Disease Diagnostic Delay Registry: SPIDER Study From Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediátrica.
A1 Jimenez-Treviño, Santiago
A1 Pujol-Muncunill, Gemma
A1 Martin-Masot, Rafael
A1 Rodriguez-Martinez, Alejandro
A1 Segarra-Canton, Oscar
A1 Peña-Quintana, Luis
A1 Armas-Ramos, Honorio
A1 Eizaguirre-Arocena, Francisco Javier
A1 Barrio-Torres, Josefa
A1 Garcia-Burriel, Jose Ignacio
A1 Ortigosa-Castillo, Luis
A1 Donat-Aliaga, Ester
A1 Crujeiras-Martinez, Vanesa
A1 Barros-Garcia, Patricia
A1 Botija-Arcos, Gonzalo
A1 Bartolome-Porro, Juan Manuel
A1 Juste-Ruiz, Mercedes
A1 Ochoa-Sangrador, Carlos
A1 Garcia-Casales, Zuriñe
A1 Galicia-Poblet, Gonzalo
A1 Oliver-Goicolea, Pablo
A1 Lorenzo-Garrido, Helena
A1 Garcia-Romero, Ruth
A1 La-Orden-Izquierdo, Enrique
A1 Perez-Solis, David
A1 Navas-Lopez, Victor Manuel
A1 Diaz-Martin, Juan Jose
A1 Martin-de-Carpi, Javier
K1 Crohn's disease
K1 Children
K1 Diagnostic delay
K1 Inflammatory bowel disease
K1 Time to diagnosis
K1 Ulcerative colitis
AB Background and Aims: Diagnostic delay (DD) is especially relevant in children with inflammatory bowel disease, leading to potential complications. We examined the intervals and factors for DD in the pediatric population of Spain. Methods: We conducted a multicentric prospective study, including 149 pediatric inflammatory bowel disease patients, obtaining clinical, anthropometric, and biochemical data. Time to diagnosis (TD) was divided into several intervals to identify those where the DD was longer and find the variables that prolonged those intervals. Missed opportunities for diagnosis (MODs) were also identified. Results: Overall TD was 4.4 months (interquartile range [IQR] 2.6-10.4), being significantly higher in Crohn's disease (CD) than in ulcerative colitis (UC) (6.3 [IQR 3.3-12.3] vs. 3 [IQR 1.6-5.6] months, p = 0.0001). Time from the visit to the first physician until referral to a pediatric gastroenterologist was the main contributor to TD (2.4 months [IQR 1.03-7.17] in CD vs. 0.83 months [IQR 0.30-2.50] in UC, p = 0.0001). One hundred and ten patients (78.3%) visited more than one physician (29.9% to 4 or more), and 16.3% visited the same physician more than six times before being assessed by the pediatric gastroenterologist. The number of MODs was significantly higher in CD than that in UC patients: 4 MODs (IQR 2-7) vs. 2 MODs ([IQR 1-5], p = 0.003). Referral by pediatricians from hospital care allowed earlier IBD diagnosis (odds ratio 3.2 [95% confidence interval 1.1-8.9], p = 0.025). Conclusions: TD and DD were significantly higher in CD than those in UC. IBD patients (especially those with CD) undergo a large number of medical visits until the final diagnosis.
PB Frontiers Research Foundation
SN 2296-2360
YR 2020
FD 2020-10-15
LK http://hdl.handle.net/10668/16592
UL http://hdl.handle.net/10668/16592
LA en
NO Jiménez Treviño S, Pujol Muncunill G, Martín-Masot R, Rodríguez Martínez A, Segarra Cantón O, Peña Quintana L, et al. Spanish Pediatric Inflammatory Bowel Disease Diagnostic Delay Registry: SPIDER Study From Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediátrica. Front Pediatr. 2020 Oct 15;8:584278
DS RISalud
RD Sep 16, 2025