RT Journal Article
T1 Spanish Pediatric Inflammatory Bowel Disease Diagnostic Delay Registry: SPIDER Study From Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediátrica.
A1 Jiménez Treviño, Santiago
A1 Pujol Muncunill, Gemma
A1 Martín-Masot, Rafael
A1 Rodríguez Martínez, Alejandro
A1 Segarra Cantón, Oscar
A1 Peña Quintana, Luis
A1 Armas Ramos, Honorio
A1 Eizaguirre Arocena, Francisco Javier
A1 Barrio Torres, Josefa
A1 García Burriel, José Ignacio
A1 Ortigosa Castillo, Luis
A1 Donat Aliaga, Ester
A1 Crujeiras Martínez, Vanesa
A1 Barros García, Patricia
A1 Botija Arcos, Gonzalo
A1 Bartolomé Porro, Juan Manuel
A1 Juste Ruiz, Mercedes
A1 Ochoa Sangrador, Carlos
A1 García Casales, Zuriñe
A1 Galicia Poblet, Gonzalo
A1 Oliver Goicolea, Pablo
A1 Lorenzo Garrido, Helena
A1 García Romero, Ruth
A1 La Orden Izquierdo, Enrique
A1 Pérez Solis, David
A1 Navas-López, Víctor Manuel
A1 Díaz Martin, Juan José
A1 Martín de Carpi, Javier
K1 Crohn's disease
K1 children
K1 diagnostic delay
K1 inflammatory bowel disease
K1 time to diagnosis
K1 ulcerative colitis
AB Background and Aims: Diagnostic delay (DD) is especially relevant in children with inflammatory bowel disease, leading to potential complications. We examined the intervals and factors for DD in the pediatric population of Spain. Methods: We conducted a multicentric prospective study, including 149 pediatric inflammatory bowel disease patients, obtaining clinical, anthropometric, and biochemical data. Time to diagnosis (TD) was divided into several intervals to identify those where the DD was longer and find the variables that prolonged those intervals. Missed opportunities for diagnosis (MODs) were also identified. Results: Overall TD was 4.4 months (interquartile range [IQR] 2.6-10.4), being significantly higher in Crohn's disease (CD) than in ulcerative colitis (UC) (6.3 [IQR 3.3-12.3] vs. 3 [IQR 1.6-5.6] months, p = 0.0001). Time from the visit to the first physician until referral to a pediatric gastroenterologist was the main contributor to TD (2.4 months [IQR 1.03-7.17] in CD vs. 0.83 months [IQR 0.30-2.50] in UC, p = 0.0001). One hundred and ten patients (78.3%) visited more than one physician (29.9% to 4 or more), and 16.3% visited the same physician more than six times before being assessed by the pediatric gastroenterologist. The number of MODs was significantly higher in CD than that in UC patients: 4 MODs (IQR 2-7) vs. 2 MODs ([IQR 1-5], p = 0.003). Referral by pediatricians from hospital care allowed earlier IBD diagnosis (odds ratio 3.2 [95% confidence interval 1.1-8.9], p = 0.025). Conclusions: TD and DD were significantly higher in CD than those in UC. IBD patients (especially those with CD) undergo a large number of medical visits until the final diagnosis.
SN 2296-2360
YR 2020
FD 2020-10-15
LK http://hdl.handle.net/10668/16592
UL http://hdl.handle.net/10668/16592
LA en
DS RISalud
RD Apr 10, 2025