TY - JOUR AU - Gallardo-Orihuela, Andrea AU - Hervás-Corpión, Irati AU - Hierro-Bujalance, Carmen AU - Sanchez-Sotano, Daniel AU - Jiménez-Gómez, Gema AU - Mora-López, Francisco AU - Campos-Caro, Antonio AU - Garcia-Alloza, Monica AU - Valor, Luis M PY - 2019 DO - 10.1038/s41598-019-55177-9 UR - http://hdl.handle.net/10668/14808 T2 - Scientific reports AB - Huntington disease (HD) is a fatal neurodegenerative disorder without a cure that is caused by an aberrant expansion of CAG repeats in exon 1 of the huntingtin (HTT) gene. Although a negative correlation between the number of CAG repeats and the age... LA - en KW - Animals KW - Brain KW - Corpus Striatum KW - Disease Models, Animal KW - Gene Expression Regulation KW - Humans KW - Huntingtin Protein KW - Huntington Disease KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Neostriatum KW - Nerve Tissue Proteins KW - Neurons KW - Nuclear Proteins KW - Phenotype KW - Transcription, Genetic KW - Transcriptome KW - Trinucleotide Repeat Expansion TI - Transcriptional correlates of the pathological phenotype in a Huntington's disease mouse model. TY - research article VL - 9 ER -