RT Journal Article T1 Leisure-Time Physical Activity, Sedentary Behaviour and Diet Quality are Associated with Metabolic Syndrome Severity: The PREDIMED-Plus Study. A1 Gallardo-Alfaro, Laura A1 Bibiloni, Maria Del Mar A1 Mascaró, Catalina M A1 Montemayor, Sofía A1 Ruiz-Canela, Miguel A1 Salas-Salvadó, Jordi A1 Corella, Dolores A1 Fitó, Montserrat A1 Romaguera, Dora A1 Vioque, Jesús A1 Alonso-Gómez, Ángel M A1 Wärnberg, Julia A1 Martínez, J Alfredo A1 Serra-Majem, Lluís A1 Estruch, Ramon A1 Fernández-García, José Carlos A1 Lapetra, José A1 Pintó, Xavier A1 García Ríos, Antonio A1 Bueno-Cavanillas, Aurora A1 Gaforio, José J A1 Matía-Martín, Pilar A1 Daimiel, Lidia A1 Micó-Pérez, Rafael M A1 Vidal, Josep A1 Vázquez, Clotilde A1 Ros, Emilio A1 Fernandez-Lázaro, Cesar Ignacio A1 Becerra-Tomás, Nerea A1 Gimenez-Alba, Ignacio Manuel A1 Zomeño, María Dolors A1 Konieczna, Jadwiga A1 Compañ-Gabucio, Laura A1 Tojal-Sierra, Lucas A1 Pérez-López, Jéssica A1 Zulet, M Ángeles A1 Casañas-Quintana, Tamara A1 Castro-Barquero, Sara A1 Gómez-Pérez, Ana María A1 Santos-Lozano, José Manuel A1 Galera, Ana A1 Basterra-Gortari, F Javier A1 Basora, Josep A1 Saiz, Carmen A1 Pérez-Vega, Karla Alejandra A1 Galmés-Panadés, Aina M A1 Tercero-Maciá, Cristina A1 Sorto-Sánchez, Carolina A1 Sayón-Orea, Carmen A1 García-Gavilán, Jesús A1 Muñoz-Martínez, Júlia A1 Tur, Josep A K1 Mediterranean diet K1 depression risk K1 metabolic syndrome severity K1 physical activity K1 sedentary behaviour AB Healthy lifestyle factors, such as physical activity (PA) and Mediterranean diet (MD), decrease the likelihood of developing metabolic syndrome (MetS). The aim of this study was to report main lifestyle components and related factors according to the MetS severity. Cross-sectional analysis was done of baseline lifestyle factors from 5739 participants with overweight/obesity and MetS features (aged 55-75 years) included in the PREDIMED-PLUS primary cardiovascular prevention randomized trial. Participants were categorized in tertiles according to a validated MetS severity score (MetSSS). Anthropometrics, visceral adiposity index, dietary nutrient intake, biochemical marker levels, as well as a Dietary Inflammatory Index and depression symptoms (Beck Depression Inventory-II) were measured. Diet quality was assessed using a 17-item energy-restricted MD questionnaire. Duration and intensity of PA was self-reported using the Minnesota-REGICOR Short Physical Activity Questionnaire. Sedentary behaviours were measured using the Spanish version of the Nurses' Health Study questionnaire. The 30 s chair stand test was also assessed. Participants with highest MetSSS showed higher values of cardiovascular risk factors (except for total cholesterol and LDL cholesterol), depression risk, sedentary and TV viewing time, and lower moderate and vigorous leisure-time physical activity (LTPA). Highest MetSSS participants tended to a pro-inflammatory dietary pattern and tended to lower MD adherence. In addition, they showed lower carbohydrate and nut intake and higher intake of protein, saturated and trans fatty acids, cholesterol, iodine, sodium, red and processed meat products, other oils different from olive oil and spirit alcoholic drinks. The highest MetS severity score was associated with lower moderate and vigorous LTPA and higher sedentary time and depression risk, as they tended to a pro-inflammatory dietary pattern and lower MD adherence. YR 2020 FD 2020-04-07 LK http://hdl.handle.net/10668/15350 UL http://hdl.handle.net/10668/15350 LA en DS RISalud RD Apr 9, 2025