TY - JOUR AU - Clemente-Postigo, Mercedes AU - Oliva-Olivera, Wilfredo AU - Coin-Aragüez, Leticia AU - Ramos-Molina, Bruno AU - Giraldez-Perez, Rosa María AU - Lhamyani, Said AU - Alcaide-Torres, Juan AU - Perez-Martinez, Pablo AU - El Bekay, Rajaa AU - Cardona, Fernando AU - Tinahones, Francisco J PY - 2018 DO - 10.1152/ajpendo.00277.2018 UR - http://hdl.handle.net/10668/13178 T2 - American journal of physiology. Endocrinology and metabolism AB - Impaired adipose tissue (AT) lipid handling and inflammation is associated with obesity-related metabolic diseases. Circulating lipopolysaccharides (LPSs) from gut microbiota (metabolic endotoxemia), proposed as a triggering factor for the low-grade... LA - en KW - fatty acid binding protein KW - human adipose tissue KW - human obesity KW - leptin KW - lipopolysaccharides KW - Adipocytes KW - Adipose Tissue KW - Adult KW - Endotoxemia KW - Fatty Acid Synthase, Type I KW - Fatty Acid-Binding Proteins KW - Female KW - Gastrointestinal Microbiome KW - Gene Expression KW - Humans KW - Inflammation KW - Intra-Abdominal Fat KW - Leptin KW - Lipogenesis KW - Lipopolysaccharides KW - Male KW - Middle Aged KW - Obesity KW - PPAR gamma KW - Stearoyl-CoA Desaturase KW - Sterol Regulatory Element Binding Protein 1 KW - Subcutaneous Fat TI - Metabolic endotoxemia promotes adipose dysfunction and inflammation in human obesity. TY - research article VL - 316 ER -