RT Journal Article
T1 Ultrasound findings of lung ultrasonography in COVID-19: A systematic review.
A1 Gil-Rodríguez, Jaime
A1 Pérez de Rojas, Javier
A1 Aranda-Laserna, Pablo
A1 Benavente-Fernández, Alberto
A1 Martos-Ruiz, Michel
A1 Peregrina-Rivas, José-Antonio
A1 Guirao-Arrabal, Emilio
K1 COVID-19
K1 Lung
K1 SARS-CoV-2
K1 Systematic review
K1 Ultrasound
AB To identify the defining lung ultrasound (LUS) findings of COVID-19, and establish its association to the initial severity of the disease and prognostic outcomes. Systematic review was conducted according to the PRISMA guidelines. We queried PubMed, Embase, Web of Science, Cochrane Database and Scopus using the terms ((coronavirus) OR (covid-19) OR (sars AND cov AND 2) OR (2019-nCoV)) AND (("lung ultrasound") OR (LUS)), from 31st of December 2019 to 31st of January 2021. PCR-confirmed cases of SARS-CoV-2 infection, obtained from original studies with at least 10 participants 18 years old or older, were included. Risk of bias and applicability was evaluated with QUADAS-2. We found 1333 articles, from which 66 articles were included, with a pooled population of 4687 patients. The most examined findings were at least 3 B-lines, confluent B-lines, subpleural consolidation, pleural effusion and bilateral or unilateral distribution. B-lines, its confluent presentation and pleural abnormalities are the most frequent findings. LUS score was higher in intensive care unit (ICU) patients and emergency department (ED), and it was associated with a higher risk of developing unfavorable outcomes (death, ICU admission or need for mechanical ventilation). LUS findings and/or the LUS score had a good negative predictive value in the diagnosis of COVID-19 compared to RT-PCR. The most frequent ultrasound findings of COVID-19 are B-lines and pleural abnormalities. High LUS score is associated with developing unfavorable outcomes. The inclusion of pleural effusion in the LUS score and the standardisation of the imaging protocol in COVID-19 LUS remains to be defined.
YR 2022
FD 2022-01-20
LK http://hdl.handle.net/10668/22190
UL http://hdl.handle.net/10668/22190
LA en
DS RISalud
RD Apr 8, 2025