RT Journal Article
T1 Validation of a prognostic score for hidden cancer in unprovoked venous thromboembolism.
A1 Jara-Palomares, Luis
A1 Otero, Remedios
A1 Jimenez, David
A1 Praena-Fernandez, Juan Manuel
A1 Font, Carme
A1 Falga, Conxita
A1 Soler, Silvia
A1 Riesco, David
A1 Verhamme, Peter
A1 Monreal, Manuel
A1 RIETE Registry, 
AB The usefulness of a diagnostic workup for occult cancer in patients with venous thromboembolism (VTE) is controversial. We used the RIETE (Registro Informatizado Enfermedad Trombo Embólica) database to perform a nested case-control study to validate a prognostic score that identifies patients with unprovoked VTE at increased risk for cancer. We dichotomized patients as having low- (≤2 points) or high (≥3 points) risk for cancer, and tried to validate the score at 12 and 24 months. From January 2014 to October 2016, 11,695 VTE patients were recruited. Of these, 1,360 with unprovoked VTE (11.6%) were eligible for the study. At 12 months, 52 patients (3.8%; 95%CI: 2.9-5%) were diagnosed with cancer. Among 905 patients (67%) scoring ≤2 points, 22 (2.4%) had cancer. Among 455 scoring ≥3 points, 30 (6.6%) had cancer (hazard ratio 2.8; 95%CI 1.6-5; p
YR 2018
FD 2018-03-20
LK http://hdl.handle.net/10668/12255
UL http://hdl.handle.net/10668/12255
LA en
DS RISalud
RD Apr 20, 2025