TY - JOUR AU - Morrugares, Rosario AU - Correa-Saez, Alejandro AU - Moreno, Rita AU - Garrido-Rodriguez, Martin AU - Muñoz, Eduardo AU - de la Vega, Laureano AU - Calzado, Marco A PY - 2019 DO - 10.1007/s00018-019-03309-9 UR - http://hdl.handle.net/10668/14634 T2 - Cellular and molecular life sciences : CMLS AB - NOTCH proteins constitute a receptor family with a widely conserved role in cell cycle, growing and development regulation. NOTCH1, the best characterised member of this family, regulates the expression of key genes in cell growth and angiogenesis,... LA - en PB - Springer KW - Cancer KW - DYRK2 KW - Degradation KW - Kinase KW - NOTCH1 KW - Phosphorylation KW - Cell Line KW - DNA Damage KW - Humans KW - Phosphorylation KW - Proteasome Endopeptidase Complex KW - Protein Domains KW - Protein Serine-Threonine Kinases KW - Protein-Tyrosine Kinases KW - Receptor, Notch1 KW - TYK2 Kinase TI - Phosphorylation-dependent regulation of the NOTCH1 intracellular domain by dual-specificity tyrosine-regulated kinase 2. TY - research article VL - 77 ER -