TY  - JOUR
AU  - Lima-Cabello, Elena
AU  - Garcia-Guirado, Francisco
AU  - Calvo-Medina, Rocio
AU  - el Bekay, Rajaa
AU  - Perez-Costillas, Lucia
AU  - Quintero-Navarro, Carolina
AU  - Sanchez-Salido, Lourdes
AU  - de Diego-Otero, Yolanda
PY  - 2016
DO  - 10.1155/2016/8548910
UR  - http://hdl.handle.net/10668/2401
T2  - Oxidative Medicine and Cellular Longevity
AB  - BACKGROUND:Fragile X syndrome is the most common genetic cause of mental disability. Although many research has been performed, the mechanism underlying the pathogenesis is unclear and needs further investigation. Oxidative stress played major roles...
LA  - en
PB  - Hindawi Publishing Corporation
KW  - Fragile X syndrome
KW  - Nitric oxide metabolism
KW  - Protein nitration
KW  - Nitric oxide synthase
KW  - Nuclear factor kappa B
KW  - Brain
KW  - Mouse model
KW  - Oxidative stress
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Animal::Disease Models, Animal
KW  - Medical Subject Headings::Diseases::Congenital, Hereditary, and Neonatal Diseases and Abnormalities::Genetic Diseases, Inborn::Genetic Diseases, X-Linked::Mental Retardation, X-Linked::Fragile X Syndrome
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Genetically Modified::Mice, Transgenic::Mice, Knockout
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::NF-kappa B
KW  - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Nitrogen Compounds::Nitrogen Oxides::Nitric Oxide
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxidoreductases Acting on CH-NH2 Group Donors::Amino Acid Oxidoreductases::Nitric Oxide Synthase
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Protein Isoforms
KW  - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::NF-kappa B::Transcription Factor RelA
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, Cyclic::Amino Acids, Aromatic::Tyrosine
TI  - An Abnormal Nitric Oxide Metabolism Contributes to Brain Oxidative Stress in the Mouse Model for the Fragile X Syndrome, a Possible Role in Intellectual Disability.
TY  - research article
ER  -