RT Generic T1 Impact of Exercise on Gut Microbiota in Obesity A1 Aragon-Vela, Jeronimo A1 Solis-Urra, Patricio A1 Ruiz-Ojeda, Francisco Javier A1 Alvarez-Mercado, Ana Isabel A1 Olivares-Arancibia, Jorge A1 Plaza-Diaz, Julio K1 gut microbiota K1 physical activity K1 health K1 obesity K1 children K1 humans K1 non-communicable diseases K1 Farnesoid x receptor K1 Chain fatty-acids K1 Physical-activity K1 Weight-loss K1 Appetite regulation K1 Body-composition K1 Adipose-tissue K1 Disease K1 Health K1 Mechanisms AB Physical activity, exercise, or physical fitness are being studied as helpful nonpharmacological therapies to reduce signaling pathways related to inflammation. Studies describing changes in intestinal microbiota have stated that physical activity could increase the microbial variance and enhance the ratio of Firmicutes/Bacteroidetes, and both actions could neutralize the obesity progression and diminish body weight. The aim of this review is to provide an overview of the literature describing the relationship between physical activity profiles and gut microbiota and in obesity and some associated comorbidities. Promoting physical activity could support as a treatment to maintain the gut microbiota composition or to restore the balance toward an improvement of dysbiosis in obesity; however, these mechanisms need to be studied in more detail. The opportunity to control the microbiota by physical activity to improve health results and decrease obesity and related comorbidities is very attractive. Nevertheless, several incompletely answered questions need to be addressed before this strategy can be implemented. PB Mdpi YR 2021 FD 2021-11-01 LK https://hdl.handle.net/10668/26212 UL https://hdl.handle.net/10668/26212 LA en DS RISalud RD Apr 6, 2025