RT Journal Article T1 Level of discomfort in critically ill paediatric patients and its correlation with sociodemographic and clinical variables, analgosedation and withdrawal syndrome. COSAIP multicentre study (Phase 2) A1 Bosch-Alcaraz, Alejandro A1 Luna-Castano, Patricia A1 Garcia-Soler, Patricia A1 Tamame-San Antonio, Marta A1 Falco-Pegueroles, Anna A1 Alcolea-Monge, Sandra A1 Fernandez Lorenzo, Rocio A1 Piqueras-Rodriguez, Pedro A1 Molina-Gallego, Irene A1 Potes-Rojas, Cristina A1 Gesti-Senar, Silvia A1 Orozco-Gamez, Rocio A1 Carmen Tercero-Cano, Maria A1 Angeles Saz-Roy, M. A1 Jordan, Iolanda A1 Belda-Hofheinz, Sylvia K1 Paediatric Intensive Care Unit K1 COMFORT K1 Infant welfare K1 Sedation K1 Withdrawal syndrome K1 Comfort behavior scale K1 Intensive-care-unit K1 Procedural pain K1 Sedation K1 Analgesia K1 Delirium K1 Reliability K1 Validity K1 Tool AB Introduction: There are clinical and sociodemographic factors that have an impact on the comfort of the critically ill paediatric patient. The main aim of this study was to determine the level of discomfort of paediatric patients admitted to different national hospitals, and to analyse its correlation with sociodemographic and clinical variables, analgosedation, and withdrawal syndrome.Methods: An observational, analytical, cross-sectional, and multicentre study was conducted in five Spanish hospitals. The level of analgosedation was assessed once per shift over a 24 h period, using a BIS sensor, and pain with scales adapted to paediatric age population. The intensity of withdrawal syndrome was determined using the Withdrawal Assessment Tool (WAT-1) scale once per shift for 3 days. Discomfort level was simultaneous assessed using COMFORT Behaviour Scale-Spanish version (CBS-S).Results: A total of 261 critically ill paediatric patients with median age of 1.61 years (IQR = 0.35-6.55) were included. An overall discomfort score of 10.79 +/- 3.7 was observed during morning compared to 10.31 +/- 3.3 observed during the night. When comparing analgosedation and nonanalgosedation groups, statistically differences were found in both shifts (chi(2) : 45.48; P= .001). At the same time, an association was observed (P PB Ediciones doyma s a SN 1695-4033 YR 2021 FD 2021-12-01 LK https://hdl.handle.net/10668/24355 UL https://hdl.handle.net/10668/24355 LA es DS RISalud RD Apr 8, 2025