TY - JOUR AU - Fields, Francisco R AU - Lee, Shaun W AU - McConnell, Michael J PY - 2016 DO - 10.1016/j.bcp.2016.12.002 UR - http://hdl.handle.net/10668/10670 T2 - Biochemical pharmacology AB - The shrinking antibiotic development pipeline together with the global increase in antibiotic resistant infections requires that new molecules with antimicrobial activity are developed. Traditional empirical screening approaches of natural and... LA - en KW - Antibiotic discovery KW - Antibiotic resistance KW - Bacteriocins KW - Essential genes KW - Genomics KW - Animals KW - Anti-Bacterial Agents KW - Drug Design KW - Drug Discovery KW - Drug Resistance, Bacterial KW - Genes, Essential KW - Genome, Bacterial KW - Humans TI - Using bacterial genomes and essential genes for the development of new antibiotics. TY - research article VL - 134 ER -