TY - JOUR AU - Jimenez, Rosario AU - Toral, Marta AU - Gómez-Guzmán, Manuel AU - Romero, Miguel AU - Sanchez, Manuel AU - Mahmoud, Ayman M AU - Duarte, Juan PY - 2018 DO - 10.1155/2018/5852706 UR - http://hdl.handle.net/10668/12758 T2 - Oxidative medicine and cellular longevity AB - Hyperglycemia induces oxidative stress and plays a substantial role in the progression of vascular diseases. Here, we demonstrated the potentiality of peroxisome proliferator-activated receptor (PPAR)β/δ activation in attenuating high glucose-induced... LA - en KW - Animals KW - Diabetes Mellitus, Experimental KW - Glucose KW - Heme Oxygenase-1 KW - Human Umbilical Vein Endothelial Cells KW - Humans KW - Hyperglycemia KW - Male KW - NAD(P)H Dehydrogenase (Quinone) KW - NADPH Oxidases KW - NF-E2-Related Factor 2 KW - Oxidative Stress KW - PPAR delta KW - PPAR-beta KW - Rats KW - Rats, Wistar KW - Reactive Oxygen Species KW - Signal Transduction KW - Superoxides TI - The Role of Nrf2 Signaling in PPARβ/δ-Mediated Vascular Protection against Hyperglycemia-Induced Oxidative Stress. TY - research article VL - 2018 ER -