TY - JOUR AU - Nicoletti, Paola AU - Aithal, Guruprasad P AU - Bjornsson, Einar S AU - Andrade, Raul J AU - Sawle, Ashley AU - Arrese, Marco AU - Barnhart, Huiman X AU - Bondon-Guitton, Emmanuelle AU - Hayashi, Paul H AU - Bessone, Fernando AU - Carvajal, Alfonso AU - Cascorbi, Ingolf AU - Cirulli, Elizabeth T AU - Chalasani, Naga AU - Conforti, Anita AU - Coulthard, Sally A AU - Daly, Mark J AU - Day, Christopher P AU - Dillon, John F AU - Fontana, Robert J AU - Grove, Jane I AU - Hallberg, Pär AU - Hernández, Nelia AU - Ibáñez, Luisa AU - Kullak-Ublick, Gerd A AU - Laitinen, Tarja AU - Larrey, Dominique AU - Lucena, M Isabel AU - Maitland-van der Zee, Anke H AU - Martin, Jennifer H AU - Molokhia, Mariam AU - Pirmohamed, Munir AU - Powell, Elizabeth E AU - Qin, Shengying AU - Serrano, Jose AU - Stephens, Camilla AU - Stolz, Andrew AU - Wadelius, Mia AU - Watkins, Paul B AU - Floratos, Aris AU - Shen, Yufeng AU - Nelson, Matthew R AU - Urban, Thomas J AU - Daly, Ann K AU - International Drug-Induced Liver Injury Consortium, Drug-Induced Liver Injury Network Investigators, and International Serious Adverse Events Consortium PY - 2016 DO - 10.1053/j.gastro.2016.12.016 UR - http://hdl.handle.net/10668/10733 T2 - Gastroenterology AB - We performed a genome-wide association study (GWAS) to identify genetic risk factors for drug-induced liver injury (DILI) from licensed drugs without previously reported genetic risk factors. We performed a GWAS of 862 persons with DILI and 10,588... LA - en KW - Anti-Fungal Agent KW - Liver Damage KW - Medication KW - Side Effect KW - Alleles KW - Antidepressive Agents KW - Antifungal Agents KW - Chemical and Drug Induced Liver Injury KW - Chromosomes, Human, Pair 2 KW - Female KW - Fenofibrate KW - Genes, MHC Class I KW - Genetic Predisposition to Disease KW - Genome-Wide Association Study KW - HLA-A Antigens KW - Humans KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors KW - Hypolipidemic Agents KW - Male KW - Middle Aged KW - Naphthalenes KW - Odds Ratio KW - Phenotype KW - Platelet Aggregation Inhibitors KW - Polymorphism, Single Nucleotide KW - Sertraline KW - Terbinafine KW - Ticlopidine KW - White People TI - Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. TY - research article VL - 152 ER -