RT Journal Article T1 Assessing Prevalence and Factors Related to Frailty in Community-Dwelling Older Adults: A Multinomial Logistic Analysis A1 Blanco-Reina, Encarnación A1 Aguilar-Cano, Lorena A1 García-Merino, María Rosa A1 Ocaña-Riola, Ricardo A1 Valdellós, Jenifer A1 Bellido-Estévez, Inmaculada A1 Ariza-Zafra, Gabriel K1 Frailty K1 Older adults K1 Polymedication K1 Osteoarticular pathology K1 Psychopathology K1 Primary care K1 Fragilidad K1 Personas mayores frágiles K1 Polimedicación K1 Artropatías K1 Psicopatología K1 Atención primaria de salud AB Frailty is an age-related clinical condition that typically involves a deterioration in the physiological capacity of various organ systems and heightens the patient's susceptibility to stressors. For this reason, one of the main research goals currently being addressed is that of characterising the impact of frailty in different settings. The main aim of this study is to determine the prevalence of Fried's frailty phenotype among community-dwelling older people and to analyse the factors associated with frailty. In this research study, 582 persons aged 65 years or more participated in this cross-sectional study that was conducted at primary healthcare centres in Málaga, Spain. Sociodemographic, clinical, functional and comprehensive drug therapy data were compiled. The relationship between the independent variables and the different states of frailty was analysed by using a multinomial logistic regression model. Frailty was present in 24.1% of the study sample (95% CI = 20.7-27.6) of whom 54.3% were found to be pre-frail and 21.6% were non-frail. The study variable most strongly associated with frailty was the female gender (OR = 20.54, 95% CI = 9.10-46.3). Other factors found to be associated with the state of frailty included age, dependence for the instrumental activities of daily living (IADL), polymedication, osteoarticular pathology and psychopathology. This study confirms the high prevalence of frailty among community-dwelling older people. Frailty may be associated with many factors. Some of these associated factors may be preventable or modifiable and, thus, provide clinically relevant targets for intervention. This is particularly the case for depressive symptoms, the clinical control of osteoarthritis and the use of polypharmacy. PB MDPI YR 2021 FD 2021-08-14 LK http://hdl.handle.net/10668/4084 UL http://hdl.handle.net/10668/4084 LA en NO Blanco-Reina E, Aguilar-Cano L, García-Merino MR, Ocaña-Riola R, Valdellós J, Bellido-Estévez I, et al. Assessing Prevalence and Factors Related to Frailty in Community-Dwelling Older Adults: A Multinomial Logistic Analysis. J Clin Med. 2021 Aug 14;10(16):3576 DS RISalud RD Apr 8, 2025