TY  - JOUR
AU  - Villar-Lorenzo, Andrea
AU  - Rada, Patricia
AU  - Rey, Esther
AU  - Marañón, Patricia
AU  - Arroba, Ana I
AU  - Santamaría, Beatriz
AU  - Sáiz, Jorge
AU  - Rupérez, Francisco J
AU  - Barbas, Coral
AU  - García-Monzón, Carmelo
AU  - Valverde, Ángela M
AU  - González-Rodríguez, Águeda
PY  - 2019
DO  - 10.1242/dmm.038810
UR  - http://hdl.handle.net/10668/14206
T2  - Disease models & mechanisms
AB  - Insulin receptor substrate 2 (IRS2) is a key downstream mediator of insulin and insulin-like growth factor 1 (IGF1) signalling pathways and plays a major role in liver metabolism. The aim of this study was to investigate whether IRS2 had an impact on...
LA  - en
KW  - Bile acids
KW  - Cholestatic injury
KW  - Fibrosis
KW  - Hepatic stellate cells
KW  - IGF1
KW  - IRS2
KW  - Animals
KW  - Bile Ducts
KW  - Cell Line
KW  - Cholestasis
KW  - Female
KW  - Hepatic Stellate Cells
KW  - Humans
KW  - Insulin Receptor Substrate Proteins
KW  - Insulin-Like Growth Factor I
KW  - Liver Cirrhosis
KW  - Mice
KW  - Mice, Knockout
KW  - Signal Transduction
TI  - Insulin receptor substrate 2 (IRS2) deficiency delays liver fibrosis associated with cholestatic injury.
TY  - research article
VL  - 12
ER  -