TY - JOUR AU - Burtness, Barbara AU - Haddad, Robert AU - Dinis, Jose AU - Trigo, Jose AU - Yokota, Tomoya AU - de-Souza-Viana, Luciano AU - Romanov, Ilya AU - Vermorken, Jan AU - Bourhis, Jean AU - Tahara, Makoto AU - Martins-Segalla, Jose Getulio AU - Psyrri, Amanda AU - Vasilevskaya, Irina AU - Nangia, Chaitali Singh AU - Chaves-Conde, Manuel AU - Kiyota, Naomi AU - Homma, Akihiro AU - Holeckova, Petra AU - Del-Campo, Josep Maria AU - Asarawala, Nirav AU - Nicolau, Ulisses Ribaldo AU - Rauch, Daniel AU - Even, Caroline AU - Wang, Bushi AU - Gibson, Neil AU - Ehrnrooth, Eva AU - Harrington, Kevin AU - Cohen, Ezra E W PY - 2019 DO - 10.1001/jamaoncol.2019.1146 UR - http://hdl.handle.net/10668/14105 T2 - JAMA oncology AB - Locoregionally advanced head and neck squamous cell cancer (HNSCC) is treated curatively; however, risk of recurrence remains high among some patients. The ERBB family blocker afatinib has shown efficacy in recurrent or metastatic HNSCC. To assess... LA - en PB - American Medical Association KW - Carboplatin KW - Squamous Cell Carcinoma of Head and Neck KW - Disease-Free Survival KW - Hypopharynx KW - Neoplasm Recurrence, Local KW - Medical Futility KW - Random Allocation KW - Oropharynx KW - Chemoradiotherapy KW - Stomatitis KW - Epithelial Cells TI - Afatinib vs Placebo as Adjuvant Therapy After Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck: A Randomized Clinical Trial. TY - research article VL - 5 ER -