RT Journal Article T1 Impact of individualized management of breakthrough cancer pain on quality of life in advanced cancer patients: CAVIDIOPAL study. A1 Tuca Rodríguez, Albert A1 Núñez Viejo, Miguel A1 Maradey, Pablo A1 Canal-Sotelo, Jaume A1 Guardia Mancilla, Plácido A1 Gutiérrez Rivero, Sonia A1 Raja Casillas, Inmaculada A1 Herrera Abián, María A1 López Bermudo, Cristina K1 Breakthrough cancer pain K1 Individualized therapy K1 Palliative care K1 Quality of life K1 Transmucosal fentanyl AB The main aim of the study was to assess the impact of individualized management of breakthrough cancer pain (BTcP) on quality of life (QoL) of patients with advanced cancer in clinical practice. A prospective, observational, multicenter study was conducted in patients with advanced cancer that were assisted by palliative care units. QoL was assessed with the EORTC QLQ-C30 questionnaire at baseline (V0) and after 28 days (V28) of individualized BTcP therapy. Data on background pain, BTcP, comorbidities, and frailty were also recorded. Ninety-three patients completed the study. Intensity, duration, and number of BTcP episodes were reduced (p  Individualized BTcP therapy improved QoL of patients with advanced cancer. Transmucosal fentanyl at low doses was the most used drug. This study was registered at ClinicalTrials.gov database (NCT02840500) on July 19, 2016. YR 2021 FD 2021-02-03 LK http://hdl.handle.net/10668/17091 UL http://hdl.handle.net/10668/17091 LA en DS RISalud RD Apr 13, 2025